21C Museum Hotel  4 stars

700 W. Main Street, Louisville, United States, 40202  show mapSave
  • Overview
  • Rooms & Availability
  • Location
  • Guest reviews
  • Facilities

Editorial review:

The novelty alone of staying in a 24-hour museum is sufficient to sell you on the idea. And then there is the fact that it is visually stunning, from the lobby which features rotating exhibits of engaging works by living artists, to the numerous pieces which adorn the halls, elevators as well as the out of this world Proof on Main restaurant. The rooms are in cool tones and sport exposed brick and all the latest gadgets, such as 42-inch HDTVs, WiFi, 500 thread count sheets) and delightfully quirky touches such as rubber duckies in the bath and silver cups.

Verified Reviews:

  • No hot water in the evening - Quiet air conditioning - Bar is fantastic
  • No pool - Free wi-fi internet - Bed was very comfortable
  • Bathroom were very nice - Food was great - Pet friendly
  • Friendly staff - Room was extremely clean - Service at breakfast was really slow
  • Wonderfully located downtown - Lobby gallery is also gorgeous - Valet parking was 15/day


The 21c Museum Hotel is situated in the heart of Museum Row in historic downtown Louisville, close to Louisville Slugger Museum and Louisville Science Center.

The four-star boutique venue with traditional Southern design features contemporary art museum, seven meeting rooms, in-house spa and fitness center.

Guests are offered 90 rooms spread over series of 19th century tobacco and bourbon warehouses, equipped with high ceilings, large windows, plush bedding, custom furniture, plush bathrobes and fully stocked mini-bar.

The property offers to have breakfast, lunch and dinner at the restaurant or in your room.

Year renovated   2006.  Number of rooms   200.

City Center Louisville - 2000 ft
Airports Louisville International (Standiford Field) (SDF) - 6.0 mi, Blue Grass (LEX) - 64.7 mi
Restaurants Luigi's Pizzeria (Cuisine: Pizza) - 100 ft, The St. Charles Exchange (Cuisine: American) - 200 ft


All rooms and suites are fitted with up-to-date amenities, including iPod docking station, poster art, 42inch HDTV flat screen television with cable channels, luxurious bedding, complimentary high-speed internet access, coffee maker, large work desks with ergonomic chair, access to the in-house spa and well-stocked mini-bar.

Dining options

The hotel restaurant serves wide range of local and international dishes, homemade pastry and bakery, and selection of refreshing drinks in attractive atmosphere.

A full breakfast is served at affordable prices. 


The meeting facilities include one large atrium for up to 120 persons, four private meeting areas from 10 to 60 persons, boardroom with audio-visual capabilities, 42inch flat screen and conference phone for up to 12 persons, and business center with state-of-the-art audio-visual equipment and wireless high-speed internet access.


The in-house spa features massage rooms, sauna, steam room and fitness facility, offering wide range of therapies, massages and treatments, as well as modern training equipment.

Additional features

The additional facilities comprise 24-hour reception, room service, airport transportation service, safe deposit box at front desk, elevator, laundry, dry cleaning, babysitting, non-smoking facilities and tour desk.

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General information



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  • Parking
  • Safe deposit box
  • Pets allowed
  • Elevator
  • ATM/Cash machine
  • Multilingual staff
  • Concierge desk
  • Storage space
  • 24-Hour Front Desk
  • Newspapers/magazines
  • Tour desk

Wireless internet is available in public areas and is free of charge.

Guest Parking

Private hotel parking is possible on site and the rate is USD 26 per day.

  • Spa & wellness center
  • Limousine service
  • Valet parking
  • Laundry
  • Dry cleaning
Dining facilities
  • Bar/Lounge
  • Restaurant
Business facilities
  • Wi-Fi Internet
  • Business center
  • Fax/photocopying
Meeting facilities
  • Meeting/banquet facilities
Facilities for people with disabilities
  • Rooms/facilities for people with disabilities
Leisure and relaxation facilities
  • Sauna
  • Fitness center
  • Bicycle rentals
  • Shiatsu massage
  • Hammam
Room facilities
  • Non-smoking rooms
  • Air conditioning
  • Room service
  • Heating
  • Tea and Coffee Facilities
  • Ironing facilities
  • Mini-refrigerator
  • Work desk
  • Mini bar
  • Balcony
  • Turndown service
  • Terrace
  • Dressing area
Living Area
  • Ergonomic chair
  • Bathtub
  • Hair dryer
  • Shower
  • Toilet
  • Private bathroom
  • Bathrobe
Kitchen facilities
  • Bottled water
  • Cable TV
  • Satellite TV
  • LCD TV
  • Analog data port
  • Voice mail
  • Speaker phone
  • AM/FM alarm clock
  • Telephone
  • Radio
  • DVD player
  • Cordless phone
  • iPod docking station



from  4 pm


until  11 am

Children and extra beds
  • Older children/adults may stay at the price of USD 30 per person per night in an extra bed. 

Pets are allowed on request.

Travelers’ questions & answers

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All rooms and suites are fitted with up-to-date amenities, including iPod docking station, poster art, 42inch HDTV flat screen television with cable channels, luxurious bedding, complimentary high-speed internet access, coffee maker, large work desks with ergonomic chair, access to the in-house spa and well-stocked mini-bar.

Luxury Double Room
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Bed type: King Size Bed
Room facilities
    Luxury Rooftop Double Room
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    Bed type: King Size Bed
    Room facilities

      21C Museum Hotel LocationWhat's nearby

      • Current hotel
      • Hotels nearby
      • Airports
      • Underground stations
      • Train stations
      • Parks
      • Tourist attractions
      • Museums
      • Convention centers
      • Stadiums
      • Food and meals
      • General

      Hover above the icons to see hotel photo and details.

      Click the hotel to go to the main hotel page.

      What's nearby

      What's nearby.

      Louisville Science Center, Louisville Slugger Museum, Kentucky Art and Craft Gallery are 100m away.

      Actors Theatre of Louisville, Kentucky International Convention Center and Louisville Gardens are 500m away.

      Muhammad Ali Center, Western KY Federal Community, W L Brown Lyons Theatre and Louisville/Jeffersonville Amtrak are 1.2km away.

      Tourist attractions
      • Actors Theatre of Louisville
        1700 ft
      • Downtown
        2000 ft
      • Louisville/Jeffersonville Amtrak
        4000 ft
      Popular areas
      • Belle of Louisville & Spirit of Jefferson
        2700 ft
      Places of interest
      Convention centers
      • It's Your Quarter Inc
        2300 ft
      Monuments and Landmarks
      Historical sites
      • Glassworks
        700 ft
      • Louisville Gardens
        2000 ft
      • Louisville Science Ctr
        400 ft
      • Arts Kentucky
        400 ft
      • 400 ft
      • Kentucky Art and Craft Gallery
        400 ft
      • Muhammad Ali Cente
        700 ft
      • Brennan House Inc
        3300 ft
      • Galerie Hertz
        4000 ft
      Universities, Institutes
      • Kentucky Tech Jefferson Campus
        2700 ft
      • Health Institute of Louisville
        3300 ft
      Medical care and Hospitals

      Local Attractions

      • Thomas Edison Butchertown House
        1.2 mi
        729 East Washington Street, Louisville
      • Falls of the Ohio State Park
        1.3 mi
        201 West Riverside Dr., Clarksville
      • Atlantis Waterpark
        1.7 mi
        515 Marriott Drive, Clarksville
      • Conrad-Caldwell House Museum (Conrad's Castle)
        1.9 mi
        1402 St. James Court, Louisville
      • Central Park
        2.0 mi
        Fourth & Magnolia Avenues, Louisville

      Near the hotel

      • Kentucky Museum of Art and Craft
        100 ft
        715 West Main St., Louisville
      • Louisville Science Center
        100 ft
        727 W. Main Street, Louisville
      • Louisville Slugger Museum & Factory
        600 ft
        800 West Main St., Louisville
      • Muhammad Ali Center
        600 ft
        144 N. Sixth Street, Louisville
      • Frazier History Museum
        900 ft
        829 West Main Street, Louisville
      • Flame Run Glass Studio and Gallery
        1000 ft
        815 W Market St, Louisville
      • Louisville Waterfront Park
        3900 ft
        231 Witherspoon, Louisville

      Restaurants Nearby

      • Luigi's Pizzeria

        69% likes this, based on 40 reviews
        Cuisine: Pizza

        100 ft
        712 W Main St

        Phone: (502) 589-0005

      • The St. Charles Exchange

        63% likes this, based on 70 reviews
        Cuisine: American
        Price Range: USD 31 - USD 50

        200 ft
        113 South 7th Street

        Phone: 502.618.1917

      • Mrs. Potter's Coffee Lounge & Cafe

        65% likes this, based on 49 reviews
        Cuisine: Coffee Shop

        300 ft
        718 W. Main St., Suite 1N

        Phone: 502-581-1867

      • Main Eatery

        64% likes this, based on 47 reviews

        300 ft
        643 W Main St

        Phone: 502-589-7200

      • Morton's - The Steakhouse

        69% likes this, based on 91 reviews
        Cuisine: Steakhouse
        Price Range: USD 60 - USD 80

        400 ft
        626 West Main Street

        Phone: (502) 584-0421

      Getting there.

      Louisville International Airport is approximately 20 minutes from the venue.

      From the airport follow signs for I-264 (Watterson Expressway) East and downtown, take the I-264 east to I-65 North, take exit 136C, follow on W. Jefferson Street to 7th Street, take right and the hotel entrance with valet parking will be three blocks up, just before Main Street.

      Getting around.

      Louisville International Airport is 10km away.

      Louisville railway station is 2.5km away.

      21C Museum Hotel Reviews

      Guest reviews are submitted by our customers after their stay at 21C Museum Hotel

      Average guest rating

      out of 10
      Based on 38 reviews

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